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How to prep your body on a glp1 medication. #wegovy #glp1 #semaglutide #tirzepatide #glp1community
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To cite: Senni N, Savall M, Cabrerizo Granados D, et al. Gut 2019;68:322-334. Read the full article here: http://dx.doi.org/10.1136/gutjnl-2017-315448. Objectives: CTNNB1-mutated hepatocellular carcinomas (HCCs) constitute a major part of human HCC and are largely inaccessible to target therapy. Yet, little is known about the metabolic reprogramming induced by β-catenin oncogenic activation in the liver. We aimed to decipher such reprogramming and assess whether it may represent a new avenue for targeted therapy of CTNNB1-mutated HCC. Conclusions: FAO induced by β-catenin oncogenic activation in the liver is the driving force of the β-catenin-induced HCC. Inhibiting FAO by genetic and pharmacological approaches blocks HCC development, showing that inhibition of FAO is a suitable therapeutic approach for CTNNB1-mutated HCC.
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Why does Ozempic cause nausea in so many people? Ozempic (semaglutide) is a GLP-1 receptor agonist used for weight loss and type 2 diabetes — but one of its most common side effects is persistent nausea. Here’s why 👇 Ozempic slows down gastric emptying, meaning food stays in your stomach longer than normal. This disruption in your digestive rhythm triggers signals through the gut-brain axis — a complex communication network between your intestines and your brain. The result? 👉 Bloating 👉 Early fullness 👉 Queasiness 👉 Nausea — sometimes severe It’s not food poisoning. It’s not anxiety. It’s your gut struggling to keep up. ✅ Ways to manage Ozempic-induced nausea: – Eat smaller meals – Opt for cold or bland foods – Sip ginger tea or chew ginger – Stay upright for 1–2 hours after eating – Start with lower doses (talk to your doctor) 📌 Whether you're taking Ozempic for weight loss or diabetes, understanding these side effects helps you stay in control. 🔔 Follow for gut-brain science, explained simply. #SemaglutideNausea #OzempicTips #WeightLossJourney #GLP1SideEffects #GutHealthMatters #MedicalEducation #ozempic #semaglutideforweightloss #ozempicweightloss #ozempicjourney #glp1 #glp1medication
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Beyond the Scales is a short podcast series hosted by Emily, and Fran, who are both Year 4 Medical Students studying in the UK. alongside Mr Lee Humphreys, a Consultant Bariatric Surgeon who practises in the UK. The aim of the podcast is to dispel common myths surrounding obesity, specifically amongst medical students and other healthcare professionals In this episode, we discuss the impact that ultra-processed foods have on our ability to control our weight. Please find the references for the discussion below; Semaglutide - https://bnf.nice.org.uk/drugs/semaglutide/#important-safety-information Orlistat - https://bnf.nice.org.uk/drugs/orlistat/ NICE guidelines for obesity management - https://www.nice.org.uk/guidance/cg189/resources/obesity-identification-assessment-and- management-pdf-35109821097925 GLP-1 and the brain - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280675/#:~:text=These%20studies%20ha ve%20also%20shown,energy%20homeostasis%20and%20autonomous%20functions. Examples of GLP-1 analogues - https://www.diabetes.org.uk/guide-to-diabetes/managing- your-diabetes/treating-your-diabetes/tablets-and-medication/incretin-mimetics Liraglutide weight loss - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358074/ Semaglutide weight loss - https://www.nejm.org/doi/10.1056/NEJMoa2032183 Tirzepatide weight loss - https://www.nejm.org/doi/10.1056/NEJMoa2206038 Summary of clinical trials for GLP-1 receptor agonists - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509428/ Semaglutide trial - https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 Patient preferences for GLP-1 receptor agonists- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483112/ FDA evaluation of reports of suicidal thoughts related to GLP-1 receptor agonists - https://www.fda.gov/drugs/drug-safety-and-availability/update-fdas-ongoing-evaluation- reports-suicidal-thoughts-or-actions-patients-taking-certain- type#:~:text=Similarly%2C%20our%20reviews%20of%20the,of%20suicidal%20thoughts%20 or%20actions. Bariatric Surgery and risk of suicide - https://pubmed.ncbi.nlm.nih.gov/30343409/ Bariatric Surgery and gallstones - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011673/#:~:text=The%20incidence%20o f%20gallstone%20formation,recommended%20to%20prevent%20gallstone%20formation Oral semaglutide phase 3 clinical trials - https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01185-6/abstract GLP-1 receptor agonist shortage - https://www.bmj.com/content/384/bmj.q28#:~:text=The%20supply%20of%20glucagon%2 Dlike,demand%20and%20off%2Dlabel%20use. GLP-1 receptor agonist shortage information - https://www.diabetes.org.uk/guide-to- diabetes/managing-your-diabetes/treating-your-diabetes/tablets-and-medication/incretin- mimetics/shortage-FAQs Unintended and adverse consequences of GLP-1 receptor agonists - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495825/ NICE guidelines Phentermine (discontinued) - https://www.nice.org.uk/guidance/discontinued/gid-tag439 New clinical trials looking at obesity medications - https://www.clinicaltrialsarena.com/features/obesity-trials-to-watch/?cf-view Weight regain after stopping semaglutide - https://pubmed.ncbi.nlm.nih.gov/35441470/ Devon 2023 Tier 3 weight management average waiting times - https://www.royaldevon.nhs.uk/media/ieibfrgr/foi-rdf1222-23-tier-3-tier-4-weight- management-services.pdf Weight loss medications and bariatric surgery - https://link.springer.com/article/10.1007/s13679-021-00425-1 This video is aimed for use as an educational video and should not be taken as medical advice. Any ideas raised within this video should be discussed with a healthcare professional before making any changes.
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Can You Drink Alcohol on Wegovy at a Party? Are you curious about the effects of alcohol while using Wegovy? In this informative video, we will discuss the implications of drinking alcohol for those on Wegovy, a medication designed to assist with weight loss. We’ll cover how Wegovy works in the body and its potential side effects, especially when combined with alcohol consumption. Understanding the relationship between Wegovy and alcohol is essential for anyone looking to manage their health effectively. We will explore how alcohol might impact gastrointestinal symptoms, blood sugar control, and cravings. Additionally, we’ll touch upon the risks associated with mixing alcohol and Wegovy, including the rare but serious condition of pancreatitis. Consulting with a healthcare provider is key to making informed decisions about alcohol while on this medication. Individual responses can vary, and professional guidance can help you navigate your health journey safely. Join us as we break down these important topics and provide you with the information you need. Don’t forget to subscribe to our channel for more helpful discussions on weight management and health-related topics. ⬇️ Subscribe to our channel for more valuable insights. 🔗Subscribe: https://www.youtube.com/@ObesityFightersClub/?sub_confirmation=1 #Wegovy #WeightLoss #HealthTips #AlcoholConsumption #BloodSugarControl #GastrointestinalHealth #WeightManagement #HealthyLiving #Semaglutide #DiabetesManagement #Cravings #Pancreatitis #PartyTips #MedicationSafety #ConsultYourDoctor About Us: Welcome to Obesity Fighters Club! Our channel is dedicated to helping you achieve your weight loss goals and embrace a healthier lifestyle. We cover a variety of topics, including effective weight loss tips, healthy eating habits, and fitness motivation tailored for all levels. Whether you're seeking fat-burning workouts or meal planning strategies for sustainable weight loss, we’ve got you covered.The content provided is for general, informational, and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.
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Attention Mitolyn Is The Most Effective Weight Loss Supplement On The Market Today
Weight loss industry is developing each day and now-a-days there are many products available in the market which promise create easiest way in order to lost your increasing weight. Now I would like to discuss on one product among them which is lipo pills.
It is mainly known as Liposuction or lipo suction. Morphine or Abbott laboratories release this product in the 1980s. This is a surgical procedure that uses a cosmetic surgeon who uses a suction machine to remove fat from specific areas like thighs, hips, and abdominies.
Generally, this operation is targeted stubborn fat. Along with that this Lipo pills also claim to have the ability to increase body metabolism that helps you to burn those extra fat rapidly, kill your appetite and burn your existing fat which result better enjoyment in daily food without any limitation.
Understanding Lipo Pills
Lipo pills are dietary supplements that might support weight loss by targeting a variety of mechanisms in the body, including thermogenic support and appetite suppression. They can contain caffeine, green tea extract and garcinia cambogia.
Lipo pills (which don’t need to contain any of the ingredients on their label) can offer a quick means to an easy end, but they’re not approved by the FDA, so no one knows if they work and they might not actually be safe to use. Do your homework before risking your health.
Potential Benefits of Lipo Pills
Others say lipo pills can help you lose weight by giving you more energy, lessening your appetite or boosting your fat-burning capacity. Your ‘basal metabolism’ – that is, the rate at which your body burns calories as you go about your daily tasks – might speed up a bit.
Furthermore, using lipo pills could suppress psychic hunger and help patients avoid overeating, which, in turn, makes it easier to remain under a dietary calorie limit. In our clinical experience, patients often find that they get a boost in drive and concentration that sustains them while dieting, which can be a goal in itself and a way to keep patients dieting long-term to avoid regaining the lost weight.
Potential Risks of Lipo Pills
Any potential benefits are countered by the side effects and risks that come with lipo pills. The most common side effects of lipo pills include insomnia, jitteriness, nausea and heart palpitations. Other people can end up with digestive issues or may be allergic to the ingredients.
Moreover, long-term studies of the consequences of lipo pills’ use are lacking, so we don’t know how they will impact your health over the long term. Will they be worth the potential problems they cause? That’s a decision only you can make – hopefully, with the help of your physician.
Are Lipo Pills Worth It?
Ultimately, everything surrounding lipo pills relies on the individual, and how well the pills work for them as a weight-loss tool is highly frankly ranging. Some people will really respond well to lipo pills, shedding the pounds to reach their target, but others will gain nothing or even feel ill.
Before you try lipo pills and invite despair later, you should first make sure that you truly are eating right and watching your eating and physical-activity behaviours. Those are the low-hanging fruit of lifestyle, and it will always be better to try to change a behaviour (and therefore a habit!) than trying to pop a pill. In the end, the hassle of convincing ourselves and others to eat right and be active is much better than resorting to outside help, such as a pill. On the flip side, the challenge with habit-creation addiction lies not only in weaning away from unhealthy habits, but also in being more mindful towards healthier alternatives.
Final Thoughts
On the whole, I’d say that lipo pills are probably not as effective as a low-fat, whole-food plant-based diet for weight loss, but they might help. Whether or not they’re worth the risks and uncertainties remains to be seen. The most prudent move is to approach them sceptically, do your research, and consult with a healthcare expert before using them for fat loss.
Overall, it would probably be healthiest to lose weight and stay healthy in the long term through a combination of balanced eating, physical exercise and ongoing behaviour changes. While taking lipo pills may temporarily aid a weight-loss programme, people shouldn’t rely on these pills and fall into a sedentary lifestyle without healthy eating habits.
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