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Orforglipron also reduced blood sugar levels in participants with type 2 diabetes A significant trial of a daily weight-loss pill has found that it helped people to shed the pounds and reduce their blood sugar levels, making it a contender to join the new wave of drugs that combat obesity and diabetes. People who took a 36mg pill of orforglipron lost an average of 7.3kg (16lbs) over nine months, according to results from a phase 3 clinical trial reported by the drug’s manufacturer, Eli Lilly, on Thursday. The trial, which enrolled 559 obese people with type 2 diabetes from the US, China, India, Japan and Mexico, also found that the daily pill reduced blood sugar levels, in some cases bringing them below the formal threshold for diabetes. Results from the trial have been eagerly awaited by health researchers. Orforglipron is a daily pill version of a GLP-1 agonist, the medication used in blockbuster weight-loss injections such as Ozempic and Wegovy. David Ricks, Eli Lilly’s chief executive, said: “As a convenient once-daily pill, orforglipron may provide a new option and, if approved, could be readily manufactured and launched at scale for use by people around the world.” In a statement accompanying the results, the company said the drug met expectations on safety, tolerability, glucose control and weight loss. While weight-loss jabs have soared in popularity, health officials believe that daily pill versions of the medicine could allow more people to control their weight and blood sugar levels. In Britain, two-thirds of adults are either overweight or living with obesity and more than 5 million people have type 2 diabetes. The 40-week trial showed that taking a daily pill of 3mg, 12mg or 36mg reduced blood sugar by 1.2% to 1.5%. During the same period, participants saw their weight drop by an average of 4.5% on the 3mg pill, 5.8% on the 12mg pill and 7.6% on the 36mg pill. The results will be presented at a meeting of the American Diabetes Association in June before publication in a peer-reviewed journal. The company said it would apply for approval to market the drug for weight management later this year and for type 2 diabetes next year. Naveed Sattar, a professor of cardiometabolic medicine at the University of Glasgow, said: “These are important results. Having new oral agents that lower glucose but also meaningfully lower weight well beyond levels seen with most existing diabetes therapies is critical to future type 2 diabetes care. Of course, one caveat is that we do not know the effects of this newer therapy on cardiovascular outcomes but this will be forthcoming in future trials.” - The Guardian
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As the obesity epidemic continues to rise, the search for effective weight loss treatments has become increasingly prevalent. One such treatment that has gained attention in recent years is Semaglutide, a medication originally developed for managing type 2 diabetes. However, studies have shown that Semaglutide can also aid in weight loss, making it an attractive option for individuals struggling to shed pounds. But, the question remains – does insurance cover Semaglutide for weight loss?
Understanding Semaglutide for Weight Loss
Semaglutide is a glucagon-like peptide-1 receptor agonist that works by mimicking the actions of a hormone called GLP-1. This hormone helps regulate blood sugar levels and has been found to reduce appetite, leading to weight loss in some individuals. In clinical trials, Semaglutide has been shown to be more effective in promoting weight loss compared to other weight loss medications currently on the market.
One of the main advantages of Semaglutide for weight loss is its ability to target multiple facets of obesity. In addition to reducing appetite, Semaglutide can also improve insulin sensitivity, reduce inflammation, and promote fat loss. This comprehensive approach makes Semaglutide a promising option for individuals looking to achieve significant weight loss and improve overall health.
While Semaglutide has shown promising results in clinical trials, it is essential to note that it is not a magical solution for weight loss. Like any medication, Semaglutide should be used in conjunction with a healthy diet and regular exercise to achieve long-lasting results. Additionally, Semaglutide may not be suitable for everyone, and consultation with a healthcare provider is necessary before starting treatment.
Insurance Coverage for Semaglutide
When it comes to insurance coverage for Semaglutide for weight loss, the answer is not always straightforward. While Semaglutide is FDA-approved for weight loss, insurance companies may have varying policies on covering the medication. Some insurance plans may require a prior authorization process, which involves providing documentation from a healthcare provider to justify the need for Semaglutide.
Another factor that can impact insurance coverage for Semaglutide is the individual’s insurance plan. Some plans may have specific exclusions for weight loss medications, while others may cover Semaglutide under certain conditions. It is essential to review your insurance policy or contact your insurance provider to understand what coverage options are available for Semaglutide.
In some cases, even if insurance does not cover Semaglutide for weight loss, there may be alternative ways to access the medication at a lower cost. Pharmaceutical companies often offer patient assistance programs or discounts for eligible individuals. Additionally, some healthcare providers may be able to help navigate insurance coverage options or provide resources for obtaining Semaglutide at a reduced price.
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