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REFERENCE for Curious Interested Listeners & Physicians (Below) 59,25Mar2025 Here’s what we’re covering in this Video Podcast: • How they work: These meds help regulate blood sugar and curb appetite, driving their popularity for weight loss. • Side effects: Nausea, diarrhea, and fatigue are common, but rare cases involve more serious issues like pancreatitis and muscle loss. • Shortages & controversies: Demand has led to pharmacy shortages, underground markets, and government crackdowns. Stay tuned for Part 2, where we’ll explore the biggest myths, long-term effects, and what research really says about these medications! • The weight loss question: They work while you’re on them, but what happens when you stop? Many regain the weight lost. • Mounjaro vs. Ozempic: Which is better? Some studies say Mounjaro leads to greater weight loss, but it’s not that simple. 1. Animal Studies Alhadeff AL, Rupprecht LE, Hayes MR. (2012). Glucagon-like peptide-1 receptor signaling in the ventral tegmental area attenuates food intake. Journal of Neuroscience, 32(25), 8112-8120. Showed GLP-1 drugs reduce food-seeking behavior by acting on brain reward areas. 2. Brain Reward Pathways Dickson SL, Shirazi RH, Hansson C, et al. (2012). The role of GLP‑1 receptor activation in the central regulation of energy balance and reward. Physiology & Behavior, 106(2), 231–238. Explains how GLP-1 receptors in the brain influence eating for pleasure, not just hunger. 3. Incretin Hormones Review Nauck MA & Meier JJ. (2018). Incretin hormones: Their role in health and disease. Diabetes, Obesity and Metabolism. Details the dual role of GLP-1 in gut and brain signaling. 4. The SURPASS-2 Trial Jastreboff, A. M., et al. (2022). Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes (SURPASS-2): A Randomized, Open-Label, Parallel-Group, Phase 3 Trial. This study and provided weight loss data for both tirzepatide (Mounjaro) and semaglutide (Ozempic). 5. The SURPASS Clinical Trials (Review and Meta-Analysis) Frías, J. P., et al. (2022). Insights from the SURPASS Clinical Trials: A Systematic Review and Meta-Analysis of Tirzepatide in Type 2 Diabetes. Diabetes, Obesity and Metabolism. Discusses how the additional GIP receptor activity might contribute to enhanced weight loss. 6. Eli Lilly (Mounjaro) https://www.lilly.com/news/media/media-kits/mounjaro https://mounjaro.lilly.com 7. Novo Nordisk (Ozempic) https://www.novonordisk.com.au/our-products-for-healthcare-professionals.html https://rss.medsinfo.com.au/no/pi.cfm?product=nopozemp In this video, we’re diving into the truth behind Mounjaro (tirzepatide) vs. Ozempic (semaglutide)—two medications originally developed for type 2 diabetes but now gaining attention for weight loss. The hype is huge, but what’s really going on? Novo Nordisk Eli Lilly

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Amanda Bynes reveals her Ozempic weight loss plan to achieve her goal of 130 lbs for flawless paparazzi shots! 🌟 Dive into her dramatic transformation, motivations, and updates on her health journey. Don’t miss her mission to avoid double chin angles with this controversial drug. Subscribe for more celebrity wellness news! #AmandaBynes #OzempicJourney #broadway Amanda Bynes, known for her iconic roles, is embracing Ozempic to slim down from 173 lbs to 130 lbs, prioritizing 'health is wealth' for perfect paparazzi angles. Get the inside scoop on her candid Instagram updates and how she’s tackling this bold transformation. Perfect for fans tracking celebrity fitness trends and Ozempic’s rising popularity! Keywords: Amanda Bynes Ozempic, Amanda Bynes weight loss, Ozempic celebrity use, paparazzi photo prep, Amanda Bynes transformation, celebrity health trends.

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The Keto Diet has been creating quite a buzz in recent years as a popular weight loss and health trend. Known for its low-carb, high-fat approach, the Keto Diet is said to help individuals achieve ketosis, a metabolic state where the body burns fat for energy instead of carbs. One of the most well-known endorsements of the Keto Diet came from the investors on the hit TV show Shark Tank. The Keto Diet became a hot topic after entrepreneurs pitched their keto-friendly products and received support from the sharks. If you’re looking to learn more about the Keto Diet as seen on Shark Tank, you’ve come to the right place.

The History of the Keto Diet

The Keto Diet, short for ketogenic diet, was originally developed in the 1920s as a medical treatment for epilepsy. It was designed to mimic the fasting state that helps reduce seizures in some patients. Over the years, the Keto Diet has gained popularity as a weight loss and health improvement strategy. By drastically reducing carbohydrate intake and increasing fats, the body switches from using glucose as its primary fuel source to burning ketones, a byproduct of fat metabolism. This shift in energy production is believed to offer numerous health benefits, including weight loss, improved energy levels, and better mental clarity.

As the Keto Diet gained mainstream attention, it caught the eye of investors on Shark Tank. Entrepreneurs who have developed keto-friendly products have successfully pitched their ideas on the show and secured partnerships with the sharks. This exposure has helped bring the Keto Diet to a wider audience and fueled interest in exploring this dietary approach as a means of improving health and promoting weight loss.

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Benefits of the Keto Diet

There are several potential benefits associated with following the Keto Diet. One of the most well-known advantages is weight loss. By reducing carb intake and increasing fat consumption, many individuals experience significant weight loss on the Keto Diet. This is due to the body’s shift into ketosis, where it burns fat more efficiently. In addition to weight loss, some people report improved energy levels, better mental focus, and reduced inflammation while following the Keto Diet.

Another benefit of the Keto Diet is its potential impact on certain health conditions. Some research suggests that the Keto Diet may be beneficial for individuals with type 2 diabetes, as it can help regulate blood sugar levels and improve insulin sensitivity. Additionally, the Keto Diet has been studied for its potential therapeutic effects on conditions such as Alzheimer’s disease, cancer, and epilepsy. While more research is needed in these areas, the Keto Diet shows promise as a potential tool for managing these health issues.

Getting Started on the Keto Diet

If you’re interested in trying the Keto Diet for yourself, there are a few key steps you can take to get started. First and foremost, it’s essential to understand the principles of the Keto Diet and how it works. This includes learning which foods to eat and avoid, as well as how to calculate your macronutrient ratios to achieve ketosis. It can be helpful to consult with a healthcare provider or nutritionist before starting the Keto Diet to ensure it’s a safe and appropriate choice for you.

Once you have a good grasp of the basics, it’s time to start making changes to your diet. This involves cutting back on carbs and increasing your intake of healthy fats, such as avocados, nuts, and olive oil. You’ll also want to include moderate amounts of protein and plenty of non-starchy vegetables to round out your meals. Many people find success on the Keto Diet by planning their meals in advance and tracking their food intake to stay within their target macronutrient ranges.

FAQ About the Keto Diet

1. Is the Keto Diet safe for everyone to try?

The Keto Diet may not be suitable for everyone, especially individuals with certain medical conditions or dietary restrictions. It’s important to consult with a healthcare provider before starting the Keto Diet to ensure it’s appropriate for your individual needs.

2. How quickly can you expect to see results on the Keto Diet?

Results on the Keto Diet can vary from person to person, but many individuals report seeing weight loss and other benefits within a few weeks of starting the diet. Consistency and adherence to the principles of the Keto Diet are key to achieving and maintaining results.

3. Are there any potential side effects of the Keto Diet?

Some people may experience side effects when first starting the Keto Diet, often referred to as the “Keto flu.” Symptoms can include fatigue, headache, and irritability as the body adjusts to using ketones for fuel. These side effects are usually temporary and can be mitigated by staying hydrated and ensuring an adequate intake of electrolytes.

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